The nucleoskeleton is a complex network comprising several mechanical structures that provide structural integrity and stability to the nucleus. They form an elastic shell at the nuclear periphery and scaffolds for localized stiffness in the viscoelastic interior; both of which are thought to serve as platforms for different genome functions.

The nuclear lamina, which is a region that lies between the inner nuclear membrane and the peripheral chromatin, is composed of a compressed lamin layer along with an array of adaptor proteins… Read more…