What processes occur during cardiac development? 2018-02-05T11:26:50+00:00

What processes occur during cardiac development?

The heart is the first functional organ to form during the development of an embryo, which, in humans, occurs during the third week post-fertilization. It primarily involves the following sequence of events: the specification of cardiac precursor cells from pluripotent embryonic stem cells and their differentiation into cardiac progenitor cells or cardiomyocytes, the organization of cardiomyocytes into a cardiac tube, followed by septation of the cardiac tube into four chambers as well as the paired arterial trunks. In the past two decades, a plethora of studies using advanced technologies and suitable animal models have provided a detailed account of the various cellular and molecular changes that take place during cardiomyocyte differentiation, the formation of the heart tube, and the development of the four cardiac chambers.

View All

Latest Findings

Protein Info