What role do formins play in epithelial junctional stability?
This study addresses the role of formins at epithelial junctions. A major formin, mDia1, is shown to be recruited to Adherens Junctions (AJs) by E-Cadherin and RhoA. This leads to the organization of actomyosin filaments around the AJs which causes an increase in junctional contractility. […]